Getting poster data...
Boris Fedorov, Leonid Zaslavsky and Tatiana Tatusova (National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA)NCBI has developed a set of analysis and visualization tools for representation of genome and protein sequence data from prokaryotic genomes. Comparative analysis include calculation of genome and protein clusters at various levels: phylogenomic species-level groups (clades) and close (at 95% identity) genome groups, global protein clusters and protein clusters within each clade. Navigation through this complex data requires multi-level visualization tools emphasizing different properties and providing adequate resolution and level of abstraction. In our ongoing project, we are working on an integrated visualization system connecting phylogenomic and phylogenetic tree representations, protein clusters and gene maps to an interactive environment. The system allows text queries for database searches, access to multiple views, data refinement or navigation to a different resolution level. In our approach to the meaningful data representation we utilize sampling algorithms providing sufficient levels of diversity and accuracy while reducing unnecessary redundancy.