Getting poster data...
Boris Fedorov, Anatoliy Kuznetsov, Victor Joukov and Tatiana Tatusova (National Center for Biotechnology Information, National Institutes of Health Bethesda, MD, 20894 USA)Many species, like Staphylococcus aureus, Salmonella enterica, and Escherichia coli have thousands of complete genome assemblies available. It is not possible to display all of them on a single web or printed page. NCBI has developed a set of tools and reports to facilitate analysis genome assemblies in the context of their neighbors within the same species. In our ongoing work we use whole genome nucleotide distances calculated by BLAST. The nucleotide difference between genomes is defined by Symmetrical Identity value, also shown as a hitplot of pairwise BLAST alignments. This presentation demonstrates options for browsing the relationships of all sequenced strains within a species. The Genome Information by Organism tool provides basic statistics of genome assemblies found using either a query or multiple browser filters, together with genome tree of neighbor assemblies. The whole species Genome tree presents the most important strains, as well as a particular strain in context of other assemblies in the species. Together these tools are powerful methods for comparative analysis of close genome assemblies within a species.