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Keiichiro Ono (University of California, San Diego, La Jolla, United States of America)Cytoscape is an open source platform for network data integration, analysis, and visualization. The goal of Cytoscape project is providing an easy-to-use network analysis/visualization tool for biologists, yet powerful enough for advanced users who wants to customize its functions. Cytoscape’s flexible plugin architecture makes this possible. With its core set of functions, users can work with interactome-size networks and integrate them with attributes such as functional annotations or expression data. Based on the data sets, Cytoscape provides flexible visualization functions including automatic network layout and mapping continuous and discrete data onto visual properties (node color, node size, edge width, etc). Besides these core functions, Cytoscape provides advanced features as plugins. Among the 30+ publicly available plugins, users can find features like access to public biological databases through web services. If necessary, they can implement their own analysis algorithms or advanced visualization ideas as plugins. Cytoscape has a large user/developer community and it is still growing.