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John Pinney (Imperial College London, London, United Kingdom)Scientific research, like many other social activities, is subject to trends. Certain research topics will become more attractive, exciting or fundable as public interests change and new experimental techniques are developed. Here we use GLASS (Gene LAyout by Semantic Similarity), a new methodology for data visualization in a whole-genome context, to explore research trends in yeast biology. Following the public release of the Saccharomyces cerevisiae genome in 1996, a rapid escalation of the number of publications per year is seen for many genes. However, this expansion is not uniform over the whole genome, revealing differences in the levels of scientific activity associated with different aspects of yeast biology.