Getting poster data...
Andrea Schafferhans, Seán O'Donoghue (Technische Universitaet Muenchen, Garching, Germany; EMBL Heidelberg, Germany)We present http://srs3d.org, a web site that allows users to easily and rapidly find and view all related structures for a given target sequence. Sequence-structure matches are retrieved from the pre-compiled high-quality structure-to-sequence alignments from the HSSP / PSSH family of databases. Searches for a keyword or identifier from Uniprot give a result table showing all sequences matching this query. An icon indicates sequence entries with structural information. Clicking on the icon opens the corresponding PSSH entry, which shows a graphical summary of all 3D structures with significant homology to the target protein. It displays the match region along with sequence annotations and the structure description, thus helping to identify the most relevant structures. Selecting a structure opens a HSSPalign entry, with sequences, alignments, the PDB structure and features from UniProt, all displayed in the Structure Viewer, which has many functions that help users to understand the relation between sequence and structure (e.g. search for sequence patterns). Furthermore, considerably enhances the view of PDB entries, since UniProt and PDB features are