Getting poster data...
Christoph Gille (Humboldt University, Berlin, Germany)jV (http://ef-site.hgc.jp/wiki/jV/index.php) is a sophisticated molecular 3D viewer, which has been developed in the PDBj, one member of the wwPDB, to display 3D structures and molecular surfaces of proteins and nucleic acids. Using simple XML descriptions, jV can also display 3D polylines and polygons like electron densities and molecular surfaces. By using the OpenGL library, jV is extremely fast and produces high quality images ready for publication. jV can be employed by other Java based programs for molecular visualization. Here we present integration into the protein alignment viewer STRAP http://3d-alignment.eu/ which allows combined visualization of protein structures and sequence position related information. For example sequence features from DAS services are readily displayed in 3D. Also disease causing mutations may be highlighted on the 3D-structure. This is useful since topographic mapping of mutations may explain the cause for loss of function: Often mutations coincide with ligand binding sites or catalytic sites. Visualization is not confined to single proteins: Several pepti