Getting poster data...
Xin Zhou, Mingchao Xie, Cydney Nielsen, Martin Hirst, Peggy Farnham, Robert Kuhn, Jingchun Zhu, Jim Kent, David Haussler, Joseph Costello, Ting Wang (1. Washington University in St. Louis, 2. BC Cancer Agency, 3. University of Southern California, 4. University of California at Santa Cruz, 5. University of California San Francisco)The Epigenomics Roadmap Project utilizes high-throughput sequencing technologies to generate “The Human Epigenome Atlas”, which contains over 600 maps of epigenetic marks in 56 cell types and counting. To help explore such huge and diverse dataset, we developed the Human Epigenome Browser, as part of the Washington University based Epigenomics Roadmap Visualization Hub (http://vizHub.wustl.edu/). It extends the UCSC Genome Browser and is built with “bigBed/bigWig” and HTML5 technologies to achieve high performance. The Browser displays genomic data as heatmaps or wiggle tracks, in parallel with samples’ metadata. Genome annotations and statistical analysis results are displayed as decorative tracks along with genomics maps. The Browser enables investigators to pan and zoom in smooth and intuitive operations, including “drag-n-move”, and “click-n-sort”. Investigators can collate data for any given genomic feature (e.g. promoters) to contrast epigenetic marks at such features. The Browser can serve as a generic browser for users’ own sequencing data. As high-throughput data become more available, we expect tools of this natu