Getting poster data...
Christian Stolte, Lars J Jensen, Heiko Horn, Sune Pretscher-Frankild, Kenneth Sabir, Seán I O’Donoghue (Garvan Institute of Medical Research, Sydney, CSIRO CMIS, Sydney, NNF Center for Protein Research, University of Copenhagen, Denmark. University of Sydney, Australia)The most convenient way to use Reflect is to install it as a plug-in to your web browser. The HTML document is retrieved by the user’s browser, then sent to the Reflect server, tagged and returned to the browser. The Reflect server at the European Molecular Biology Laboratory keeps in RAM a large dictionary with names and synonyms for 4.3 million small molecules, and for 1.5 million proteins from 373 organisms. When tagging an HTML document, the server finds all occurrences of these synonyms and returns a slightly modified version of the HTML document to the user’s browser—the only difference is that all matching protein, gene and small-molecule names are now tagged and highlighted. Clicking on a tagged small-molecule name opens a summary popup that shows two-dimensional structures from PubChem and interaction partners from STITCH. Clicking on a tagged protein or gene name opens a popup that shows synonyms, the complete amino acid sequence of the longest transcript, domains, a representative three-dimensional structure, principal interaction partners, and known subcellular location. The popup also has hyperlinks to the gene entry and to related abstracts.