Getting poster data...
Catherine Leroy (Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge. CB10 1SA UK)Next Generation Sequencing Technologies have been successfully applied to the field of cancer genetics revolutionising our understanding of cancer. In order to take advantage of the vast amounts of data from these technologies, it is essential that data summaries and interfaces are developed to efficiently present the data to the research scientist. As part of our mutation detection pipeline, we have developed a series of visualisation tools including CANDI which summarises the data from a tumour sample using a series of graphical displays, rainfall plots and heat maps. Recently, we have developed a Copy Number Viewer which allows scientists to visualise Copy Number changes for multiple cancer samples. The group has also produced a series of genomic summaries as part of the COSMIC database (Catalogue of Somatic Mutations In Cancer) which includes Circos plots, a tissue browser and gene mutation histogram. As the throughput and size of NGS datasets increase the interfaces will need be refined and optimised to integrate these larger datasets. Here we are covering the visualisation tools we have come up with so far.