Getting poster data...
Audrey M. Michel, Gearoid Fox, Anmol Kiran, Christof De Bo, Patrick B.F. O’Connor, Stephen M. Heaphy, James P.A. Mullan, Claire A. Donohue, Romika Kumari, Desmond G. Higgins, Pavel V. Baranov (Biochemistry Department, University College Cork, Ireland; Conway Institute, University College Dublin, Ireland; HOWEST University College West Flanders, Bruges, Belgium)Ribosome profiling (ribo-seq) is a recently developed technique that provides Genome Wide Information on Protein Synthesis (GWIPS) in vivo. It is based on the deep sequencing of ribosome protected mRNA fragments which allows the ribosome density along all mRNA transcripts present in the cell to be quantified. Since its inception, ribo-seq has been carried out in a number of eukaryotic and prokaryotic organisms. Due to the increasing interest in ribo-seq, there is a pertinent demand for a dedicated ribo-seq genome browser. Therefore we have developed GWIPS-viz, an online genome browser for viewing published ribosome profiling data (http://gwips.ucc.ie/). GWIPS-viz is based on the UCSC Genome Browser. Ribo-seq tracks coupled with mRNA-seq tracks are currently available for human, mouse, zebrafish, nematode, yeast, plants (Arabidopsis thaliana), Bacteria (Escherichia coli K12, Bacillus subtilis), Human cytomegalovirus and Bacteriophage lambda. Our objective is to continue generating ribo-seq tracks from published ribosome profiling data so that they can be readily viewed in GWIPS-viz by the scientific community.