Getting poster data...
William J.R. Longabaugh (Institute for Systems Biology, Seattle WA USA)Using BioFabric (www.BioFabric.org) to display the gene regulatory network for Escherichia coli K-12; data are from RegulonDB (regulondb.ccg.unam.mx). The network contains 1786 genes, six heterodimer complexes, and 4266 edges. In BioFabric, nodes are represented as horizontal lines instead of as points, allowing the edges to be depicted as highly organized parallel vertical line segments. The top two stripes shown here are details of the top edge of the full network, shown at the bottom. We continue to explore new ways of laying out the nodes in a BioFabric network, including the organization depicted here. Source nodes are laid out in partial order in the very top rows, while target nodes are laid out below them ordered by their degree. Within the sets of nodes of equal degree, the ordering of the source nodes drives the layout. In this depiction, BioFabric "shadow links", which fill the right half of the network, allow us to study the structure of the inputs into the target nodes.