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Catherine Laplace (Benoist-Mathis Lab, Dept. of Microbiology & Immunobiology 77, Avenue Louis Pasteur . HMS NRB - Room1052K Boston, MA 02115 United States)The Immunological Genome Project is a consortium of immunologists and computational biologists who aim, using shared and rigorously controlled data generation pipelines, to exhaustively chart gene expression profiles and their underlying regulatory networks in the mouse immune system. The project encompasses the innate and adaptive immune systems, surveying all cell types of the myeloid and lymphoid lineages with a focus on primary cells directly ex vivo. These are analyzed through different states of differentiation and maturation, activating responses, effector stages, tissue localization, age and genetic variation. These data support the computational reconstruction of the genetic regulatory networks in the immune system. ImmGen is a public resource, and its data displays are actively used by the Immunology community. The ImmGen team has developed novel modes of graphic representation, for both desktop and mobile supports, custom interactive tools that are framed around specific questions that a wet biologist might have, rather than providing simple data access. These tools have been developed over time and are in continuous evolution.