Getting poster data...
Kenneth Sabir, Dr Fabian Buske, Christian Stolte, Prof. Seokhee Hong, Prof. Susan Clark, Dr Sean O’Donoghue (Garvan Institute of Medical Resaerch, Sydney, Australia, University of Sydney, Sydney, Australia)Increasing data points to the importance of the three-dimensional structure of chromosomes, for example groups of co-expressed genes are believed to occur in close proximity due to the physical winding of the chromosomes, even though they may appear distant within the one-dimensional string of nucleotide residues. Recent experimental techniques, such as Hi-C and ChIA-PET, provide large amounts of genome-wide distance constraint connection information for the biologist to comprehend. We present Rondo, an interactive web tool for chromosome structure visualisation. Rondo uses a SQL database to pre-calculate clusters of connections at multiple resolutions to provide a responsive user experience.