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Bharathi Reddy Kunduru†, Sanjana Anilkumar Nair†, Shivangi Sachdeva# and Thenmalarchelvi Rathinavelan* (Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Telangana, India-502285.)The inherent conformation of polysaccharides possess major challenge to determine/predict their 3D structure; despitetheir importance in various biological processes in all the organisms. Capsular polysaccharides (K antigen) are long-chain polysaccharides that make up the capsules of encapsulated Gram-negative bacteria. They help bacteria to escape fromhost defense mechanisms. Here, we have developed a manually curated 3D structures’ database for 72 K antigens from various serotypes of Escherichia coli and developed an organized repository namely EK3D, which can be accessed by www.iith.ac.in/EK3D/. Using the Cartesiancoordinate’s translation method, multimers of all 72 K antigens of E. coli can be generated of any desired length and torsion angles. Subsequently, generated modelscan be downloaded and used in docking studies or as starting model for NMR structure refinement.