Getting poster data...
Florence Wang and Scott Chandry (CSIRO Australia)Microbial genomics and associated molecular technologies provide the underpinning knowledge about the organisms of importance in food safety studies. The challenges in microbial genomic data visualisation are: (1) many existing genome visualisation tools (e.g. GBrowse, CMap and CiVi) are not applicable to microbial comparative genomics; (2) many existing genome visualisation libraries do not have a user friendly interface (e.g. CIRCOS and GenomeDiagram) or are already outdated (e.g. BRIG). For microbial genomic data analysis, the similarities and differences between a limited number of microbial genomes need to be frequently compared and visualised. Typically, this is done by drawing a BLAST ring diagram. BLAST (Basic Local Alignment Search Tool) generates numeric values for the degree of relatedness between query and reference genomes. This result is then plotted as “ring diagram”: concentric circles around coordinates of a reference sequence. Conserved genes are presented as solid sections of circle while missing or weakly related sections are lighter in colour or absent. Web-BRIG has been developed to facilitate this task.