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Christopher Fucile(1), Christopher Tipton(2), James Kobie(3), Inaki Sanz(2), Alexander Rosenberg(1) (University of Alabama at Birmingham, Birmingham AL, USA(1); Emory University, Atlanta GA, USA(2); University of Rochester Medical Center, Rochester NY, USA(3))B cells have the capacity to encode a massively diverse antibody repertoire through V(D)J gene recombination during maturation as well as further diversification through somatic hypermutation during an immune response. The ability to study B cell receptor repertoires has much potential for advancing research in vaccines, autoimmunity, infectious disease, diagnostics as well as for addressing fundamental questions in adaptive immunity. We have built a bioinformatics pipeline and set of visualization tools to analyze next-generation sequencing data enabling the study of B cell receptor repertoires. This type of data presents unique challenges in visualization because of many different features to represent (e.g. diversity, gene-usage, mutation statistics, isotype distributions, relatedness between cell types or across time), and different scales (from global repertoire-level characteristics to single lineage-level sequence analysis). We present examples of repertoire visualization solutions based on data from several recent studies.